Polyethylene glycol 3350 for treatment of childhood constipation

Polyethylene glycol 3350 without electrolytes is a safe, effective, and well-tolerated option for treatment of constipation in children. A 3-day course of PEG 3350 at a dose of 1.0 to 1.5 g/kg/d can be used for fecal disimpaction. For maintenance therapy, a starting dose of 0.4 to 0.8 g/kg/d can be initiated then titrated to maximum, depending on effectiveness of therapy and severity of side effects. Parents should be educated about potential rare side effects, including flatulence, loose stool, nausea, vomiting, and abdominal cramping.

 

출처  : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682301/